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Patients should be cautioned that alcohol and other CNS depressants may produce an additive CNS depression when taken with this product and should be avoided. Methadone, or opioid substitution treatment, helps wean addicts off hardcore drugs, but inflexible barriers and a "risk averse culture" has left consumers terrified, angry and, in some cases, dead. If you have any questions or thoughts about our infographic, feel free to post them in the comments section at the end of the page. Methadone should be administered with particular caution to patients already at risk for development of prolonged QT interval (e.g., cardiac hypertrophy, concomitant diuretic use, hypokalemia, hypomagnesemia). It also helps to reduce withdrawal symptoms in people addicted to heroin or other narcotic drugs without causing the "high" associated with the drug addiction.
If too large a dose of the opioid antagonist is given to a dependent person, it will result in withdrawal symptoms (possibly severe). These factors, combined with sedation, have been linked to the causation of extensive dental damage.[31][32] Overdose[edit] Most people who have overdosed on methadone may show some of the following symptoms: Miosis (constricted pupils)[33] Vomiting[34] Hypoventilation (breathing that is too slow/shallow)[33] Drowsiness,[33] sleepiness, disorientation, sedation, unresponsiveness Skin that is cool, clammy (damp), and pale[33] Limp muscles,[33] trouble staying awake, nausea Unconsciousness[33] and coma[33] Death[34] The respiratory depression of an overdose can be treated with naloxone.[30] Naloxone is preferred to the newer, longer acting antagonist naltrexone. Clarity detox (ioot) is a great program to assist you to get clean and stay clean.
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If you miss your doses for longer than 3 days in a row, call your doctor for instructions. Comments: -May be administered IV, IM or subcutaneously, although the absorption of IM or subcutaneous injections has not been well studied and appears to be unpredictable; local tissue reactions may occur. -Oral methadone is not indicated as an as-needed analgesic; due to increased risk of overdose and death with this long-acting opioid, its use is limited to chronic pain management. This growth deficit does not appear to persist into later childhood. For Short-Term Detoxification For patients preferring a brief course of stabilization followed by a period of medically supervised withdrawal, it is generally recommended that the patient be titrated to a total daily dose of about 40 mg in divided doses to achieve an adequate stabilizing level. To date, methadone maintenance therapy has been the most systematically studied and most successful,[citation needed] and most politically polarizing,[citation needed] of any pharmacotherapy for the treatment of people with drug addiction. If side effects, such as weight loss or loss of appetite, become severe or bothersome, talk to your doctor for specific recommendations.
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This is best shown in a 2011 study published Pharmacology Biochemistry and Behavior. Now, I will not provide conversion info for methadone...ever!
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Special-Risk Patients Methadone should be given with caution, and the initial dose reduced, in certain patients such as the elderly and debilitated, and those with severe impairment of hepatic or renal function, hypothyroidism, Addison's disease, prostatic hypertrophy, or urethral stricture. Read More » Selecting a Top Comprehensive Treatment Center Selecting a top methadone treatment clinic that best meets your specific needs is one of the most important steps on the path back from addiction. Take your time in this stage and consider the different facilities so that you know all of your options before you proceed. Read More I tapered down to 160mgs of methadone in the end, I would take 600-800mgs of morphine to feel good enough. In addition, parenteral drug abuse is commonly associated with transmission of infectious diseases such as hepatitis and HIV. Sorry for the slight delay in some clips, if you want the episode and time of these ... Most methadone treatment programs dose by computer equipment that requires liquid. Calling 800-530-0431 will connect you with a methadone counselor who can answer your questions about the website or treatment if necessary.Itʼs possible that these automated requests were sent from another user on your network. People have a higher chance of addiction or abuse if they are or have been addicted to or abused other medications, street drugs, or alcohol, or if they have a history of mental problems. Itʼs also possible that your computer has been infected with a Spambot virus thatʼs using your computer to gather information. It is important to note that you should never take this prescription medication unless you have the consent of a medical professional.
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