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The bioavailability and elimination half-life of methadone are subject to substantial interindividual variability. Be sure your doctor knows if you also take stimulant medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. The highest dose of Methadone that should be used for replacement therapy when treating severe opioid addiction is 160 mg. Read More I tapered down to 160mgs of methadone in the end, I would take 600-800mgs of morphine to feel good enough. Methadone should be administered with extreme caution to patients with conditions accompanied by hypoxia, hypercapnia, or decreased respiratory reserve such as: asthma, chronic obstructive pulmonary disease or cor pulmonale, severe obesity, sleep apnea syndrome, myxedema, kyphoscoliosis, and central nervous system (CNS) depression or coma. Since methadone often enables those suffering from opioid addiction to live balanced, productive lives in recovery, the benefits are great.

Milliliters (mL or ml) and liters(L) are measures of volume. Much like the opiate addiction affects everyone in a negative way, everyone benefits when the addiction is under the control of a qualified methadone maintenance program with medication administered by a methadone center. The duration of methadone treatment ranges from a few months to several years, or even lifelong. It can vary depending on how the pharmacy mixes the methadone solution but there are usually 10mg of methadone per ml.

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I'm addicted myself and have done reports, taken classes, haveother junky friends. In cases where methadone is prescribed for pain, the relief the drug provides can lead to chemical dependency in a person suffering from chronic pain, which is why some physicians are hesitant to prescribe methadone to their patients at all. Many substances can also induce, inhibit or compete with these enzymes further affecting (sometimes dangerously) methadone half-life.

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Help opioid dependent individuals locate your clinic. Other side effects that may commonly occur include anxiety, nervousness, restlessness, insomnia, weakness, drowsiness, dry mouth, nausea, vomiting, diarrhea, constipation, and decreased sex drive. Metabolism Methadone is primarily metabolized by N-demethylation to an inactive metabolite, 2-ethylidene-1,5- dimethyl-3,3-diphenylpyrrolidene (EDDP).

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The only cases where it should be used is it if it is prescribed by a doctor for harrowing conditions when the doctor believes that the drug is the only suitable drug, or for replacement therapy for opioid treatment. How many 10 mg of oxycodone equall 10 mg of methadone? There are no accurate charts that tell you if you take 50mg of Methadone that will equal 60 mgs of Morphine. A: Methadone is in a drug class called opiate or narcotic analgesics. It was not until studies performed at the Rockefeller University in New York City by Professor Vincent Dole, along with Marie Nyswander and Mary Jeanne Kreek, that methadone was systematically studied as a potential substitution therapy. YES YOU CAN BUT IT BURNS REAL BAD IF YOU MISS AND IT TOTALLY DESTROYS YOUR VEINS. The only time any doctor is obligated to treat you is if you're in life threatening danger. Listen sir/mam, NOBODY will be completely comfortable during opiate detox, if you are so concerned about this than I dont think it is a good idea for you to come off in the first place. Drug Abuse And Dependence Methadone hydrochloride oral concentrate contains methadone, a potent Schedule II opioid agonist. In 2009, six times as many people died due to methadone overdose than in 1999. Please help support Alcohol & Drug Services in your local community Donate & Support ADS!

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