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Credit: Howcast Methadone Effects question 3 Side Effects Methadone slows down your reactions, making you appear more lethargic and your movements more exaggerated. Many people have successfully overcome their addiction by using methadone during detoxification and maintenance programs. You might also suffer from mood swings, particularly as your body's supply of methadone gets low.

Its molecular formula is C21H27NO•HCl and it has a molecular weight of 345. Patients should be advised that methadone is a potential drug of abuse.

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Metabolism Methadone is primarily metabolized by N-demethylation to an inactive metabolite, 2-ethylidene-1,5- dimethyl-3,3-diphenylpyrrolidene (EDDP). It's uncommon for tablets to be crushed and injected, but even the injectable solution can cause problems, especially if the same needle is used with multiple people or for multiple doses. Without a chance to explain, consumers were kicked off for positive urine tests or bad behaviour, some had been reported to the New Zealand Transport Authority after having a single drink at a party and others had their doses halved without warning, he claimed. "I have heard so many hideous stories out there, someone's got to do something," he said. "My friends are dying." The withdrawal from methadone is accepted to be worse then heroin.

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Its use for the treatment of addiction is usually strictly regulated. If too large a dose of the opioid antagonist is given to a dependent person, it will result in withdrawal symptoms (possibly severe). Common side effects may include feeling anxious, nervous, or restless; insomnia; feeling weak or drowsy; and dry mouth, nausea, vomiting, diarrhea, constipation, loss of appetite. When it is time to stop taking this medication, your medical team can lead you through the process so that you are able to deal with the symptoms accordingly.

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You may report side effects to FDA at 1-800-FDA-1088. S. federal regulations require the oral form in addiction treatment programs.[54] Information leaflets included in packs of UK methadone tablets state that the tablets are for oral use only and that use by any other route can cause serious harm. Acute Abdominal Conditions The administration of opioids may obscure the diagnosis or clinical course of patients with acute abdominal conditions. NMDA receptors have a very important role in modulating long-term excitation and memory formation. The public clinics are generally cheaper to attend. Peak methadone levels in milk occur approximately 4 to 5 hours after an oral dose. The greatest concentrations of clinics are in California, Maryland, New York, and New Jersey. Methadone reduction, called detoxification, are suitable for persons who wish to completely stop using drugs. Com I have some articles that may lead you to some helpful answers. ... When taking methadone liquid or tablets, always remember to follow the dosage directions provided to you by your physician or clinic.

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