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Retrieved November 26, 2015, from Abadinsky, H., & Abadinsky, H. (2014). Food and Drug Administration issued a caution about methadone, titled “Methadone Use for Pain Control May Result in Death.” The FDA also revised the drug's package insert. Gennadiy Onishchenko, Chief Sanitary Inspector, claimed in 2008 that health officials are not convinced of the treatment's efficacy.

LIFE-THREATENING QT PROLONGATION; QT interval prolongation and serious arrhythmia (Torsades de pointes) have occurred during treatment with methadone. Read More Why is 150 methadone liquid not stopping my cravings and I take up to 300 on my take home day, what's going on with me? Careful monitoring is recommended when using methadone in patients with a history of cardiac conduction abnormalities, those taking medications affecting cardiac conduction, and in other cases where history or physical exam suggest an increased risk of dysrhythmia.

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You can enter your geographic area & find a care manager, who can help assess the situation & work with you on this. ... Meds given rectally are absorbed much faster than orally. I want her to get off the drugs and into some sort of treatment for her cancer. Short-term Detoxification: -For a brief course of stabilization followed by a period of medically supervised withdrawal, titrate to a total daily dose around 40 mg per day in divided doses; after 2 to 3 days, gradually decrease the dose at 2-day intervals maintaining sufficient dose to keep withdrawal symptoms at a tolerable level. My question is, why is the 200 mil not holding me till the next mornings dose at this new clinic when at the old clinic the 120 mil held me till the next morning dose.

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Many other opioid drugs are far more deadly and dangerous than Methadone is, and that is why this drug is frequently used to wean people off of these other dangerous narcotics. Methadone clinics are now operating in OTP settings of stand-alone clinics, hospitals, and health care centers that may be publicly funded to reduce the costs of treatments to the individual. Drugs that block narcotic (opioid) receptors including pentazocine (Talwin), nalbuphine (Nubain), naloxone (Narcan), butorphanol (Stadol) and buprenorphine (Subutex) can lead to withdrawal symptoms.

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Besides weakened respiratory and cardiac functions, methadone users may suffer from the following long-term medical conditions or disorders affecting various other major organs and systems of the body: Whole Body: headaches, weakness, and water retention Central Nervous System: confusion, disorientation, euphoria, depression and listlessness, sleep disturbances Endocrinal System: hypogonadism or low testosterone level, a condition that impairs growth and development in males during puberty Gastrointestinal System: abdominal pain, constipation, dry mouth Metabolic System: low potassium or magnesium levels, weight gain Blood: low platelet count that causes the blood to clot slowly after an injury, bruising, internal bleeding Kidneys: urine retention, difficulty urinating Reproductive System: reduced sexual drive, reduced sperm production, abnormal absence of menstruation in women Skin: rashes, hives, severe itching that can lead to sores Not all methadone users exhibit the adverse effects of the drugs to the same degree. The baby may experience methadone withdrawal if breastfeeding is discontinued suddenly. Many individuals don’t even know where to start looking when it comes to finding methadone clinics in their area. Other side effects with methadone include abdominal pain, loss of appetite, constipation, dry mouth and tongue swelling. Cessation of chronic pain therapy: -In physically-dependent patient: Gradually reduce dose every 2 to 4 days Cessation of opiate-dependence therapy: -There is considerable variability in the rate at which patients taper off; abrupt discontinuation is not advised. -Dose reductions should generally be in increments of less than 10% every 10 to 14 days. Prolonged use or abuse may produce one or more of the following side effects: Tolerance that compels users to take more of the drug to experience the same degree of high Physical dependence that causes withdrawal symptoms like stomach cramps, diarrhea, and bone and muscle pain Addiction that may stem from physical dependence Lung and respiratory problems Cardiac problems Neurological effects like decline in cognitive functionality Menstrual problems in women Continued use of methadone still keeps a user dependent on opioids.

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