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Upon its release, the drug was advertised as an all-purpose pain medication. Cessation of chronic pain therapy: -In physically-dependent patient: Gradually reduce dose every 2 to 4 days Cessation of opiate-dependence therapy: -There is considerable variability in the rate at which patients taper off; abrupt discontinuation is not advised. -Dose reductions should generally be in increments of less than 10% every 10 to 14 days.

I came down 10mg a month until 80mg then 5mg a month until 20mg, then 1mg a week, I am down to 11mg and I feel fine! You should not take more methadone than prescribed You also should not take methadone more often than prescribed by your doctor.

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Methadone when taken with drugs that slow brain function, such as alcohol and barbiturates (phenobarbital), can increase the effects of these drugs. For more specific information, consult with your doctor or local pharmacist for guidance based on your health status and current medications, particularly before taking any action.

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Would you like to make it the primary and merge this question into it? Excretion The elimination of methadone is mediated by extensive biotransformation, followed by renal and fecal excretion. Methadone when taken with drugs that slow brain function, such as alcohol and barbiturates (phenobarbital), can increase the effects of these drugs. More expensive but less strict guidelines to follow. Although some of these side effects are more commonly seen in the case of an overdose, the following groups of people are more prone to experiencing these effects: Those who are not tolerant to the drug Those who suffer from lung diseases like chronic obstructive pulmonary disease (COPD), emphysema, or chronic bronchitis Those who suffer from cardiac conditions like irregular heartbeat Those who are weak or malnourished The elderly Those who have taken the drug with other respiratory suppressants like alcohol, prescription or non-prescription medicines that contain alcohol, sedatives, sleeping pills, tranquilizers, muscle relaxants, or opioid-based pain medicine Those who are suffering from mental illnesses and are on anti-anxiety or anti-depressant medication Those who have taken it with other street drugs Those who have a head injury or are suffering from any condition that increases the pressure in the brain Other Effects of Methadone on the Body and the Brain A survey carried out amongst a cross-section of methadone clients discovered that they generally have poorer health than non-methadone users. The methadone maintenance treatment program must be approved by the state and federal governments and must treat patients according to specific federal and state laws and must be accredited.

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Metabolism Methadone is primarily metabolized by N-demethylation to an inactive metabolite, 2-ethylidene-1,5- dimethyl-3,3-diphenylpyrrolidene (EDDP). Methadone is associated with the loss of menstruation in a very small percentage of women. If you are referring to liquid methadone, 1 ml is equal to 10 mg. If this is the case, youʼll just need to enter the CAPTCHA code once, and weʼll be able to distinguish between you and the other users on your IP address. While the drug does not produce a high in the same manner as heroin, it can be abused to cause the same effects as most opiates: sedation, relaxation, and reduction of anxiety. Distr. by: West-Ward Pharmaceuticals Corp., Eatontown, NJ 07724. Oxycodone (Oxycontin, Percocet) 10mg.............. Methadone causes dry mouth, reducing the protective role of saliva in preventing decay.

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