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This action is for to drop by 20% of methadone every 24hours. The medication is monitored by nursing staff and is prescribed by a physician.

However, an expert review of published data on experiences with methadone use during pregnancy by the Teratogen Information System (TERIS) concluded that maternal use of methadone during pregnancy as part of a supervised, therapeutic regimen is unlikely to pose a substantial teratogenic risk (quantity and quality of data assessed as “limited to fair”). Read More My issue is that I have found out through my experience in taking liquid methadone that it helps my fibro pain for a long period of time..one dose lasts 24hrs! Diskets (methadone)." Cebert Pharmaceuticals Inc, Birmingham, AL. Involuntary withdrawal was the "very last resort a clinician would make in a desperate attempt to prevent death - not cause it," CDHB chief of psychiatry Dr Sue Nightingale said.

More Info Around methadone as pain killer

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Most cases involve patients being treated for pain with large, multiple daily doses of methadone, although cases have been reported in patients receiving doses commonly used for maintenance treatment of opioid addiction. Precautions US REMS: The US FDA requires a Risk Evaluation and Mitigation Strategy (REMS) for EXTENDED-RELEASE (ER) AND LONG-ACTING (LA) OPIOID ANALGESICS including DOLOPHINE and methadone hydrochloride tablets.

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Even more Information About side effects of methadone maintenance

Some of the symptoms associated with an overdose include: Shallow breathing Confusion Cold skin Clammy skin Weak pulse Fainting Drowsiness Important Information Just the same as other narcotic medications, there are side effects of methadone. This is generally established by a simple urine sample. The only way to gain weight is to increase caloric intake.

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One published study in pregnant hamsters indicated that a single subcutaneous dose of methadone ranging from 31 to 185 mg/kg (the 31 mg/kg dose is approximately 2 times a human daily oral dose of 120 mg/day on a mg/m² basis) on day 8 of gestation resulted in a decrease in the number of fetuses per litter and an increase in the percentage of fetuses exhibiting congenital malformations described as exencephaly, cranioschisis, and “various other lesions.” The majority of the doses tested also resulted in maternal death. Methadone can cause weight loss or weight gain in some patients. However, the truth it is a much maligned medication. Monitor for respiratory depression, especially during initiation or following a dose increase. Tolerance is the need for more medicine to achieve the same pain relief. Methadone may be habit-forming, even at regular doses. This should be considered when prescribing or dispensing methadone hydrochloride oral concentrate in situations where the clinician is concerned about an increased risk of misuse, abuse, or diversion. The greatest concentrations of clinics are in California, Maryland, New York, and New Jersey. The only cases where it should be used is it if it is prescribed by a doctor for harrowing conditions when the doctor believes that the drug is the only suitable drug, or for replacement therapy for opioid treatment. Conditions for Distribution and Use of Methadone Products for the Treatment of Opioid Addiction Code of Federal Regulations , Title 42, Sec 8 METHADONE PRODUCTS WHEN USED FOR THE TREATMENT OF OPIOID ADDICTION IN DETOXIFICATION OR MAINTENANCE PROGRAMS, SHALL BE DISPENSED ONLY BY OPIOID TREATMENT PROGRAMS (AND AGENCIES, PRACTITIONERS OR INSTITUTIONS BY FORMAL AGREEMENT WITH THE PROGRAM SPONSOR) CERTIFIED BY THE SUBSTANCE ABUSE AND MENTAL HEALTH SERVICES ADMINISTRATION AND APPROVED BY THE DESIGNATED STATE AUTHORITY. Methadone can also help reduce withdrawal symptoms in people addicted to heroin or other narcotic drugs without causing the "high" associated with the drug addiction.

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