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While not restricted to adults, this treatment method is generally not considered for people under the age of 18. Overdosage & Contraindications OVERDOSE Signs And Symptoms Serious overdosage of methadone is characterized by respiratory depression (a decrease in respiratory rate and/or tidal volume, Cheyne-Stokes respiration, cyanosis), extreme somnolence progressing to stupor or coma, maximally constricted pupils, skeletal-muscle flaccidity, cold and clammy skin, and sometimes, bradycardia and hypotension.

The highest MG of methadone that I have seen people successfully walk off and stay off methadone is around 15mg's. Upon its release, the drug was advertised as an all-purpose pain medication. Many have serious side effects, especially if taken incorrectly.

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In fact, injection of methadone does not result in a "rush" as with some other strong opioids such as morphine or hydromorphone, because its extraordinarily high volume of distribution causes it to diffuse into other tissues in the body, particularly fatty tissue; the peak concentration in the blood is achieved at roughly the same time, whether the drug is injected or ingested.[citation needed] Oral medication is usually preferable because it offers safety, simplicity and represents a step away from injection-based drug abuse in those recovering from addiction. There is an entirely separate 40mg Methadose pill, but the DEA has recently restricted it to opiate abuse treatment centers only.

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Reductions in ejaculate volume and seminal vesicle and prostate secretions have been reported in methadone-treated individuals. Read More well the only one he can touch will be the xanax..im on methadone also for pain management.. been on these both the same time 5 yrs...before the xanax and methadone was on klonpin 4 mgs aday for 12 yrs for panic attacks..... what is the ratio if he changes me to klonpin..i take between 2. Read More ยป Selecting a Top Comprehensive Treatment Center Selecting a top methadone treatment clinic that best meets your specific needs is one of the most important steps on the path back from addiction. In fact, injection of methadone does not result in a "rush" as with some other strong opioids such as morphine or hydromorphone, because its extraordinarily high volume of distribution causes it to diffuse into other tissues in the body, particularly fatty tissue; the peak concentration in the blood is achieved at roughly the same time, whether the drug is injected or ingested.[citation needed] Oral medication is usually preferable because it offers safety, simplicity and represents a step away from injection-based drug abuse in those recovering from addiction. Methadone hydrochloride USP is a white, crystalline material that is water-soluble.

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The public clinics are generally cheaper to attend. For a precaution they gave him the morphine for a day and a half. So a dose 100 times that, taken by someone not tolerant to it, can actually kill bypassing any "high" or euphoria, will reduce oxygen to brain and other organs, lower heart rate, and depress respiration after taking such a dose. Cases of QT interval prolongation and serious arrhythmia (torsades de pointes) have been observed during treatment with methadone. The physician must remember, however, that methadone is a longacting depressant (36 to 48 hours ), whereas opioid antagonists act for much shorter periods (one to three hours). Read More Levorphanol (Dromoran) 300mg............ Drug use and abuse: A comprehensive introduction (8th ed.). Methadone is used to treat moderate to severe pain that has not been effectively treated by non-narcotic pain medications. If you are elderly or in poor health, then your dose may be similar to that of people under 18. A longer half-life frequently allows for administration only once a day in Opioid detoxification and maintenance programs.

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