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Over time, this may cause a toxic buildup of the drug. According to prescribing information, for people taking methadone for the treatment of pain, there is a chance of addiction or abuse.

The use of heroin and the illicit use of prescription opiates are also associated with erectile dysfunction. As I vomit and shat myself in my yard from methadone detox, I remember wishing I was a heroin or any other kind of addict. Besides weakened respiratory and cardiac functions, methadone users may suffer from the following long-term medical conditions or disorders affecting various other major organs and systems of the body: Whole Body: headaches, weakness, and water retention Central Nervous System: confusion, disorientation, euphoria, depression and listlessness, sleep disturbances Endocrinal System: hypogonadism or low testosterone level, a condition that impairs growth and development in males during puberty Gastrointestinal System: abdominal pain, constipation, dry mouth Metabolic System: low potassium or magnesium levels, weight gain Blood: low platelet count that causes the blood to clot slowly after an injury, bruising, internal bleeding Kidneys: urine retention, difficulty urinating Reproductive System: reduced sexual drive, reduced sperm production, abnormal absence of menstruation in women Skin: rashes, hives, severe itching that can lead to sores Not all methadone users exhibit the adverse effects of the drugs to the same degree. However, metabolism rates vary greatly between individuals, up to a factor of 100,[48][49] ranging from as few as 4 hours to as many as 130 hours,[50] or even 190 hours.[51] This variability is apparently due to genetic variability in the production of the associated cytochrome enzymes CYP3A4, CYP2B6 and CYP2D6.

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Methadone can cause weight loss or weight gain in some patients. These include the maternal use of illicit drugs, other maternal factors such as nutrition, infection, and psychosocial circumstances, limited information regarding dose and duration of methadone use during pregnancy, and the fact that most maternal exposure appears to occur after the first trimester of pregnancy.

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Methadone is available in traditional pill, sublingual tablet, and two different formulations designed for the person to drink. Effectiveness[edit] While methadone clinics are generally considered to be effective treatment options for patients addicted to opioids, especially when other interventions have failed, there is controversy surrounding the placement of methadone clinics. Furthermore, opioids produce effects which may obscure the clinical course of patients with head injuries.

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Besides, methadone has been proven to effectively reduce the incidence of heroin-overdose deaths, crime rates amongst heroin addicts, and spread of AIDS and other diseases caused due to using infected needles. Updated May 18, 2018 in Methadone 82 REPLIES SHARE RSS Liquid Methadone dose 70Mg once a day I currently take 70mgs of liquid Methadone once a day, but I used to take two 10mg tablets of Methadone twice a day. A sudden stop in usage could lead to several withdrawal symptoms. Do not stop or change the amount of medication you take without talking to your doctor first. With the liquid it is much easier to make sure it is consumed. I was given a bottle of orange liquid from a family member who says it's methadone from hospice. A: Methadone is a narcotic analgesic or pain reliever that is similar to morphine. Most people I talk to will recommend just going all the way down to 1mg and avoid any discomfort. This action is for to drop by 20% of methadone every 24hours. While not restricted to adults, this treatment method is generally not considered for people under the age of 18. The only trick to this is to make sure the correct dosages are prescribed via a reputable conversion chart. Always read and follow the complete directions and warnings on OTC medications and discuss their use with your healthcare provider before taking them. Methadone disposition was not substantially altered.

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