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Besides weakened respiratory and cardiac functions, methadone users may suffer from the following long-term medical conditions or disorders affecting various other major organs and systems of the body: Whole Body: headaches, weakness, and water retention Central Nervous System: confusion, disorientation, euphoria, depression and listlessness, sleep disturbances Endocrinal System: hypogonadism or low testosterone level, a condition that impairs growth and development in males during puberty Gastrointestinal System: abdominal pain, constipation, dry mouth Metabolic System: low potassium or magnesium levels, weight gain Blood: low platelet count that causes the blood to clot slowly after an injury, bruising, internal bleeding Kidneys: urine retention, difficulty urinating Reproductive System: reduced sexual drive, reduced sperm production, abnormal absence of menstruation in women Skin: rashes, hives, severe itching that can lead to sores Not all methadone users exhibit the adverse effects of the drugs to the same degree. More often, methadone clinics are offered in private OTP facilities that have been certified by the SAMHSA to provide methadone treatments in intensive outpatient rehab centers, physician’s offices, and other affiliated and accredited hubs.

Methadone hydrochloride, artificial cherry flavor, citric acid anhydrous USP, FD&C Red No 40, D&C Red No 33, methylparaben NF, polaxamer 407 NF, propylene glycol USP, propylparaben NF, purified water USP, sodium citrate dihydrate USP, sucrose NF. . Is liquid methadone and methadone pills the same? LOL. (Sorry, had to throw in some comic relief here. The drug takes the form of either a tablet, powder, or liquid that a person can ingest to experience relief from chronic pain. For this reason, reputable clinics start their patients on a safe dose and then increase the medication level gradually as the patient gets adjusted to the medication. If you try to use the same amount in milligrams you are likely to overdose.

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Zidovudine Experimental evidence demonstrated that methadone increased the AUC of zidovudine which could result in toxic effects. Effectiveness[edit] While methadone clinics are generally considered to be effective treatment options for patients addicted to opioids, especially when other interventions have failed, there is controversy surrounding the placement of methadone clinics.

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5 mg every 12 hours -Monitor for signs of sedation and respiratory depression; consider a lower dose of the concomitant CNS depressant. They give it to people like me with pill problems and then you can never get off the stuff. If used correctly, methadone can be a very helpful h.r.t. but rarely does it work out that way. The Centers for Disease Control (CDC) attributes about 5,000 deaths each year to methadone overdose, and the problem is rapidly growing. An autopsy report confirmed Dave died from blood poisoning on March 12, after injecting himself with an infected needle.

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Indications & Dosage INDICATIONS For detoxification treatment of opioid addiction (heroin or other morphine-like drugs). Those who do prescribe methadone often take extra care to monitor their patients’ prescriptions and watch for signs of misuse that could indicate a developing dependency. The more water they add, the more different. it will taste. Special-Risk Patients Methadone should be given with caution, and the initial dose reduced, in certain patients such as the elderly and debilitated, and those with severe impairment of hepatic or renal function, hypothyroidism, Addison's disease, prostatic hypertrophy, or urethral stricture. Also, the daily dose, severity of the pain, the patient's degree of opioid tolerance, and age and medical status of the patient should be taken into account. People that experience side effects during methadone maintenance treatment tend to feel them worst during the first weeks and months of treatment. From ORAL Methadone to PARENTERAL Methadone: -Start with a 2:1 ratio of oral to parenteral (e.g., oral methadone 10 mg to parenteral methadone 5 mg) From Other Chronic Opioids to PARENTERAL Methadone: -Individualize dose taking into account the patient's prior opioid exposure, general medical condition, concomitant medications, and anticipated breakthrough medication use. -Manufacturer's product information may be consulted for tables that aid in converting chronic pain patients from oral morphine doses to oral and parenteral methadone doses.

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