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Deaths have been reported during conversion from chronic, high-dose treatment with other opioid agonists. So, methadone can be used as a pain reliever and as part of drug addiction detoxification and maintenance programs. The drug takes the form of either a tablet, powder, or liquid that a person can ingest to experience relief from chronic pain.

Gender The use of methadone has not been evaluated for gender specificity. Cases of QT interval prolongation and serious arrhythmia (torsades de pointes) have been observed during treatment with methadone.

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Reported studies have generally compared the benefit of methadone to the risk of untreated addiction to illicit drugs. Methadone clinics dispense liquid methadone diluted with water instead of pills because its much more difficult to hide an ounce of liquid in your mouth and sneak it out of the clinic (to spit out and save, or give to someone else) than a pill. The duration of methadone treatment ranges from a few months to several years, or even lifelong. A high degree of “opioid tolerance” does not eliminate the possibility of methadone overdose, iatrogenic or otherwise.

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However, the lowest dose of Methadone is about 10 mg. Itʼs also possible that your computer has been infected with a Spambot virus thatʼs using your computer to gather information. Other adverse reactions include the following: (listed alphabetically under each subsection) Body as a Whole: asthenia (weakness), edema, headache Cardiovascular:(also see WARNINGS: Cardiac Conduction Effects): arrhythmias, bigeminal rhythms, bradycardia, cardiomyopathy, ECG abnormalities, extrasystoles, flushing, heart failure, hypotension, palpitations, phlebitis, QT interval prolongation, syncope, T-wave inversion, tachycardia, torsade de pointes, ventricular fibrillation, ventricular tachycardia Digestive: abdominal pain, anorexia, biliary tract spasm, constipation, dry mouth, glossitis Hematologic and Lymphatic: reversible thrombocytopenia has been described in opioid addicts with chronic hepatitis Metabolic and Nutritional: hypokalemia, hypomagnesemia, weight gain Nervous: agitation, confusion, disorientation, dysphoria, euphoria, insomnia, seizures Respiratory: pulmonary edema, respiratory depression (see WARNINGS: Respiratory Depression) Skin and Appendages: pruritis, urticaria, other skin rashes, and rarely, hemorrhagic urticaria Special Senses: hallucinations, visual disturbances Urogenital: amenorrhea, antidiuretic effect, reduced libido and/or potency, urinary retention or hesitancy Maintenance on a Stabilized Dose During prolonged administration of methadone, as in a methadone maintenance treatment program, there is usually a gradual, yet progressive, disappearance of side effects over a period of several weeks. I went off methadone cold turkey from 65 mg and it was hell..in my opinion there is little difference in w/d from 10mg to 65 mg in terms of w/d..others may disagree but I don't care. methadone has a very long 1/2 life..meaning it build itself up in your system.. Besides weakened respiratory and cardiac functions, methadone users may suffer from the following long-term medical conditions or disorders affecting various other major organs and systems of the body: Whole Body: headaches, weakness, and water retention Central Nervous System: confusion, disorientation, euphoria, depression and listlessness, sleep disturbances Endocrinal System: hypogonadism or low testosterone level, a condition that impairs growth and development in males during puberty Gastrointestinal System: abdominal pain, constipation, dry mouth Metabolic System: low potassium or magnesium levels, weight gain Blood: low platelet count that causes the blood to clot slowly after an injury, bruising, internal bleeding Kidneys: urine retention, difficulty urinating Reproductive System: reduced sexual drive, reduced sperm production, abnormal absence of menstruation in women Skin: rashes, hives, severe itching that can lead to sores Not all methadone users exhibit the adverse effects of the drugs to the same degree.

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I am just so thankful that we have this option now. Eating more fruits, vegetables, and whole grains is a healthy way to put on weight. It is important to note that you should never take this prescription medication unless you have the consent of a medical professional. The typical Methadone dose or the average methadone dose for the first one is around 20 mg. As with any prescription medication, it is not suggested that you miss a dose. As with most medications, there are many benefits to using methadone, particularly for those in recovery from opioid abuse; however, these benefits come along with various risks. The bioavailability and elimination half-life of methadone are subject to substantial interindividual variability. Methadone hydrochloride USP is a white, crystalline material that is water-soluble. It is my believe everyone would do best by finding their personal level of methadone's as for Mg as everyone is different. I am just so thankful that we have this option now. Stigmas surrounding these clinics, however, may still prevent them from certain communities. They were METHADONE DISKETTES 40MG, they also had DOLOPHINE 5MG and 10MG. The changes were expected to improve the quality of care provided in an OTP with increased professional discretion and individualized treatment plans, increasing the focus on performance outcomes, and expanding the availability of opioid addiction treatments to more individuals who would benefit from the life saving services they offer.

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